Anti-NLRP3/NALP3 Monoclonal Antibody [clone: 4.62]

ADIPAG20B0014C100EA 0 CNY
ADIPAG20B0014C100
Anti-NLRP3/NALP3 Monoclonal Antibody [clone: 4.62]
抗体
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).

  • Stable for at least 1 year after receipt when stored at -20°C.

Purified from concentrated hybridoma tissue culture supernatant.

Purity: >95% (SDS-PAGE)

Type:
Antigen: NLRP3/NALP3
Clonality: Monoclonal
Clone: Cryo-2
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human, Mouse
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